Self-blinding citizen science to explore psychedelic microdosing

After a long process, this Self-blinding study conducted by Balázs Sziget and the Centre for Psychedelic Research at Imperial College London is published.

The study – the largest placebo-controlled trial on psychedelics to date – used a ‘self-blinding citizen science’ approach, where members of the public who were already microdosing implemented their own placebo control following online instructions. The results from the trial may influence future studies in real-world settings.

Szigeti and his colleagues designed a citizen science study where individuals who were already microdosing could participate online. First, the 191 participants followed a setup procedure that mixed placebo pills with microdose ones. After the setup, the participants had a set of capsules without knowing which were placebo and which were microdose. The authors call this process ‘self-blinding’, as participants lost knowledge of which drug they were taking. The setup included barcodes which, when scanned, linked to the study’s IT infrastructure and allowed the researchers to track who had taken microdoses or placebos. The participants then filled out surveys about their experiences and completed online cognitive tests, while they took the pills over a four-week period. Read the official publication here>>

Imperial College London Publication

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